Professor Friend studied medicine at Cambridge and St Thomas’s Hospital and after qualifying trained as a surgeon in London and Cambridge before undertaking a period of research at the University of Cambridge under the supervision of Professor Sir Roy Calne.
In 1988 he was appointed Visiting Assistant Professor of Surgery at Indiana University Medical Center, USA, where he was responsible for initiating a programme of liver transplantation. He returned to the UK in 1989 to take up the post of University Lecturer (Honorary Consultant) in the University Department of Surgery at Cambridge. He was the Clinical Director of the Cambridge Transplant Unit and also a Fellow and Director of Studies in Medicine at Magdalene College, Cambridge.
In 1999 he was appointed to the post of Professor of Transplantation at the University of Oxford and Consultant Transplant and Hepatobiliary Surgeon at the Oxford University Hospitals NHS Trust. At that time he was also appointed Director of the Oxford Transplant Centre.
Since Professor Friend came to Oxford the numbers and types of transplant have increased. The Unit now undertakes, kidney, kidney and pancreas, pancreas alone, islet and intestinal transplants. Oxford is the largest (in terms of numbers of transplants carried out each year) pancreas transplant unit in the world.
Peter's research interests lie primarily in novel applications of normothermic organ perfusion, ranging from its use for extracorporeal support to preservation and repair prior to transplantation. He has published over 25 papers on the topic of normothermic perfusion, the basis of the OrganOx technology, as well as in the areas of clinical transplantation, immunosuppression, monoclonal antibodies, xenotransplantation, liver perfusion and aspects of general surgery.
Peter is one of two academic founders of OrganOx and has been its medical director since April 2008, being primarily responsible for the pre-clinical and clinical trials of OrganOx's patented normothermic organ perfusion technology.
Susan Fuggle was awarded her Doctor of Philosophy in transplant immunology and immunogenetics by the University of Oxford, after graduating with BSc and MSc degrees in Biochemistry and Medical Biochemistry, respectively, from the University of Manchester, UK. She has conducted research in histocompatibility and transplantation for many years. In 2000 she was appointed to a Consultant Clinical Scientist post at the Oxford Transplant Centre, where she directs the Transplant Immunology and Immunogenetics Laboratory which supports the transplant programmes within the Oxford Radcliffe Hospitals (ORH) NHS Trust. She is a Reader in Transplant Immunology at the University of Oxford, actively involved in research into transplantation. Her research interests include biomarkers of allograft dysfunction and ischaemia /reperfusion injury. Dr Fuggle is also the Scientific Advisor to Organ Donation and Transplantation, a division of NHS Blood and Transplant, having been appointed to the role at the predecessor organisation, UKTSSA, in 1995. She has a major interest in organ allocation and chaired the Kidney Advisory Group Allocation Task Force which resulted in the implementation of the 2006 UK National Kidney Allocation Scheme.
Dr Fuggle is a Fellow of the Royal College of Pathologists and currently a member of its Ethics Committee. She is currently the Chair of the British Society of Histocompatibility and Immunogenetics, a member of the European Federation for Immunogenetics Standards Committee and has previously served terms as a Councillor of the British Transplantation Society.
Consultant Transplant & Vascular Access Surgeon
James Qualified from Southampton University in 2000 and undertook postgraduate surgical training in the Wessex Deanery where his training focused on vascular and transplantation surgery. He completed his training in 2010 and was appointed to a consultant post in Oxford in September of that year, starting work at OUH NHS Trust in the October as a transplant and access surgeon.
James’s clinical work includes elective operating vascular access surgery sessions, transplantation and organ retrieval. He holds a number of peripheral pancreas assessment clinics in Portsmouth, Plymouth and Dorchester and has access clinics in Reading and Oxford. He is the lead for vascular access and pancreas transplantation. James is a Medical Educationalist with interest in undergraduate and postgraduate education programmes and training. He undertook a Master’s Degree in Education at the University of Winchester. His thesis was around the quality of surgical training post and formed part of the Department of Health’s evaluation of the new surgical curriculum. He worked briefly with DoH on the development and implementation of ‘Unfinished Business and MMC’. Currently he looks after all trainees that rotate through the Oxford Transplant Centre.
He trained for six years as a nephrologist and transplant physician at the Western Infirmary in Glasgow. Subsequently he worked as a Consultant Nephrologist with a special interest in transplantation at the University Hospital of North Staffordshire. During this period he developed an interest in non-adherence in young adult transplant recipients and transition of care from paediatric to adult care. He established a joint transition process with Birmingham Children's Hospital.
In 2002, Dr Harden joined the Oxford Kidney Unit and Transplant Centre and has continued to pursue his interest in transition, having established joint clinics with Great Ormond Street and Evelina Children's Hospitals in London. He is clinical advisor to the National Health Service in the UK on adolescent transition and young adult services in patients with ESRD. He runs a unique community-based young adult transplant service in Oxford.
In addition Paul Harden is interested in malignancy post-transplantation and the impact of targeted immunosuppression reduction. He is Chief Investigator of the RESCUE (UK) trial of immunosuppression modulation for squamous cell skin cancer post-transplantation. He is currently working with a European consortium on development of a trial of cell therapy to allow immunosuppression reduction.
Consultant Transplant Nephrologist
Phil Mason qualified from Guy's Hospital in 1979 and after junior doctor posts mainly in London, he trained in nephrology and transplantation at Hammersmith Hospital. He undertook immunology research leading to a PhD following which he was appointed Clinical Lecturer and then Senior Lecturer and Honorary Consultant in 1994. He moved to Oxford in 1995.
He has been the clinical lead for nephrology since 2009 and has a major interest in transplantation. He established the antibody incompatible transplant programme in Oxford and is an investigator on several nephrology and transplant studies. He sits on various national council related bodies including the NHSBT Kidney Advisory Group and the Living Donor Kidney Transplant 2020 Strategy Implementation Group.
Professor of Transplantation Biology and Honorary Consultant Transplant Surgeon, Nuffield Department of Surgical Sciences, University of Oxford, United Kingdom.
Professor of Transplant Surgery, University Medical Centre Groningen, The Netherlands.
Rutger J. Ploeg was born in The Hague in the Netherlands and educated at the University of Leiden. During his medical education he followed electives in Indonesia, Toronto and Cambridge. He was trained as a surgeon at the Leiden University Medical Centre. During his research fellowship in Madison at the University of Wisconsin with Dr. F.O. Belzer he became interested in organ donation, ischemia & reperfusion injury and preservation in transplantation. He was involved in the experimental studies and clinical introduction of the UW solution and received his PhD cum laude at the University of Leiden in 1991. After his clinical ASTS fellowship at the University of Wisconsin Hospital & Clinics, he was appointed consultant surgeon in 1994 at the University Medical Centre Groningen in the Netherlands and became a Professor of Surgery in 2001. He served the European Society for Organ Transplantation as Secretary and was elected President of ESOT in 2009.
Until May 2011 he was Head of the Division of Abdominal and Transplant Surgery in Groningen. In June 2011 he accepted a Chair at the University of Oxford in Transplantation Biology and works as Honorary Consultant Transplant Surgeon in the Oxford Transplant Centre. Recently he was appointed chair of the BRC Working Group Transplantation in Oxford and as National Clinical Lead for Organ Retrieval with NHSBT Blood and Transplant.
In the past decade Rutger Ploeg has intensively focused and published with his group on how the number and quality of donor organs and their viability can be improved.
He is currently coordinating a national consortium with NHSBT in the UK to investigate quality in Organ Donation and an international consortium in Europe to study preservation (EU7FW; COPE)
Srikanth Reddy was appointed as Consultant Hepatopancreaticobiliary and Transplant Surgeon at Oxford in 2010. He trained in Oxford and Birmingham. He did three years of research in Oxford and obtained a PhD in normothermic perfusion for organ preservation in liver transplantation. He is lead for Clinical Governance in the Transplant Division, where his role is to ensure safe clinical practice. His research interests include strategies to reduce ischaemia reperfusion injury in liver, pancreas and kidneys.
Consultant Nephrology and Transplant Medicine
Oxford Kidney Unit, Oxford University Hospitals
Dr Sharples was appointed as consultant in renal medicine in 2007, and works full-time in nephrology and transplant medicine. He is medical lead for the Oxford pancreas transplant programme, one of the largest in Europe. The programme is active in clinical research, with local and national collaborations. He is a member of Renal Registry Transplant Study group, Renal Medicine Specialist Advisory Committee and the Renal Associations guidelines committee. He acts on external reference groups for Kidney Research UK and NICE NHS Evidence.
Consultant Transplant Surgeon
Sanjay is the Lead for Living Donor surgery & Kidney Transplantation. His areas of expertise are in transplantation of Kidney, pancreas & small bowel, Laparoscopic Surgery including living donor surgery, Dialysis Access and General Surgery. After completing his surgical residency at the All India Institute of Medical Sciences, New Delhi, Sanjay trained in Liverpool & Oxford and obtained his Specialist Registration in 2005. Since then he has been associated with the Oxford Transplant Centre and has been integral in its transformation in to a major transplant centre in Europe.