New technology

OrganOx

Conventional cold preservation involves storage of the liver at 4°C, using a non-physiological perfusion solution that aims to minimise liver degradation. By contrast, warm preservation seeks to re-create an environment that mimics the human body by continuously perfusing at physiological pressures and flows with oxygen-carrying red cells at 37°C and providing nutrition. The liver is therefore functional during the preservation period, producing bile, metabolizing glucose and maintaining a physiological pH. This enables objective assessment of organ performance prior to transplant, extended preservation times.

OrganOx® limited is a medical device company with a mission to increase the quality and supply of organs for transplantation.

OrganOx’s first product, the OrganOx metra® enables the repair, preservation and viability assessment of livers prior to transplantation, for up to 24 hours using normothermic oxygenated blood.

 

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© Oxford Transplant Foundation 2015 (Last Updated:22/05/23 )

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OrganOx

Conventional cold preservation involves storage of the liver at 4°C, using a non-physiological perfusion solution that aims to minimise liver degradation. By contrast, warm preservation seeks to re-create an environment that mimics the human body by continuously perfusing at physiological pressures and flows with oxygen-carrying red cells at 37°C and providing nutrition. The liver is therefore functional during the preservation period, producing bile, metabolizing glucose and maintaining a physiological pH. This enables objective assessment of organ performance prior to transplant, extended preservation times.

OrganOx® limited is a medical device company with a mission to increase the quality and supply of organs for transplantation.

OrganOx’s first product, the OrganOx metra® enables the repair, preservation and viability assessment of livers prior to transplantation, for up to 24 hours using normothermic oxygenated blood.

 

We need everyone's help. Turn good intentions into action and sign up today by visiting the
We need everyone's help. Turn good intentions into action and sign up today by visiting the